Patrick Dempsey, Denzel Washington and George Clooney.Photo:ABC; NBC/Getty (2)

ABC; NBC/Getty (2)
Meet PEOPLE’s Sexiest Doctors Alive! Well, the Hollywood version, that is.This year’s Sexiest Man Alive,Patrick Dempsey, found one of his most beloved characters inGrey’s Anatomy’s Dr. Derek Shepherd, and he is in good company, as many of the previous Sexiest Men Alive also scrubbed in for a role.From Dempsey’s 11-season tenure on the long-running medical drama toMatthew McConaughey’s turn as a charming pediatrician and beyond, here are some of the sexiest onscreen doctors.
Meet PEOPLE’s Sexiest Doctors Alive! Well, the Hollywood version, that is.
This year’s Sexiest Man Alive,Patrick Dempsey, found one of his most beloved characters inGrey’s Anatomy’s Dr. Derek Shepherd, and he is in good company, as many of the previous Sexiest Men Alive also scrubbed in for a role.
From Dempsey’s 11-season tenure on the long-running medical drama toMatthew McConaughey’s turn as a charming pediatrician and beyond, here are some of the sexiest onscreen doctors.
01of 15Patrick DempseyPatrick Dempsey.Karen Neal/Disney General Entertainment Content via GettyIn arguably his most beloved and well-known role,this year’s Sexiest Man Aliveplayed Dr. Derek Shepherd onGrey’s Anatomyfor 11 seasons before his character’s heartbreaking death. While it had been years since he had appeared on the long-running medical drama, during season 17,McDreamyreturned for some special cameos.“No one knew until I showed up on set that day,” Dempseysaid of the surprise at the time.“And then we were really concerned that someone would take a picture and it would be out somehow, but we managed to keep it a secret, which was pretty phenomenal.”
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Patrick Dempsey
Patrick Dempsey.Karen Neal/Disney General Entertainment Content via Getty

In arguably his most beloved and well-known role,this year’s Sexiest Man Aliveplayed Dr. Derek Shepherd onGrey’s Anatomyfor 11 seasons before his character’s heartbreaking death. While it had been years since he had appeared on the long-running medical drama, during season 17,McDreamyreturned for some special cameos.
“No one knew until I showed up on set that day,” Dempseysaid of the surprise at the time.“And then we were really concerned that someone would take a picture and it would be out somehow, but we managed to keep it a secret, which was pretty phenomenal.”
02of 15Denzel WashingtonDenzel Washington.Herb Ball/NBCU Photo Bank/NBCUniversal via GettyThoughPEOPLE’s 1996 Sexiest Man Alivemade his big screen debut in 1981’sCarbon Copy,his career really took off when he landed the role of Dr. Philip Chandler onSt. Elsewhere— a part he played for all of the show’s six seasons from 1982 to 1988.
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Denzel Washington
Denzel Washington.Herb Ball/NBCU Photo Bank/NBCUniversal via Getty

Herb Ball/NBCU Photo Bank/NBCUniversal via Getty
ThoughPEOPLE’s 1996 Sexiest Man Alivemade his big screen debut in 1981’sCarbon Copy,his career really took off when he landed the role of Dr. Philip Chandler onSt. Elsewhere— a part he played for all of the show’s six seasons from 1982 to 1988.
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Paul Rudd

PEOPLE’s 2021 Sexiest Man Alivestepped into the role of Dr. Isaac “Ike” Herschkopf on the 2021 series,The Shrink Next Door, in whichhe played a therapist to Will Ferrell’s Martin “Marty” Markowitz.
04of 15Brad PittBrad Pitt.NBC/NBCU Photo Bank via GettyIn 2020, amid the COVID-19 pandemic,PEOPLE’s two-time Sexiest Man Aliveportrayed Dr. Anthony FaucionSaturday Night Live,addressing the American public as the then-leader of the White House Coronavirus Task Force.
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Brad Pitt
Brad Pitt.NBC/NBCU Photo Bank via Getty

NBC/NBCU Photo Bank via Getty
In 2020, amid the COVID-19 pandemic,PEOPLE’s two-time Sexiest Man Aliveportrayed Dr. Anthony FaucionSaturday Night Live,addressing the American public as the then-leader of the White House Coronavirus Task Force.
05of 15George ClooneyGeorge Clooney.Sven Arnstein/NBCU Photo Bank/NBCUniversal via GettyGeorge Clooney, who was crowned PEOPLE’s Sexiest Man in 1997 and 2006, appeared as Dr. Doug Ross on the medical dramaERstarting in 1994. Twelve years after the show wrapped, the cast came together for an epic Zoom reunion and Clooney admitted that his wife, Amal,is not Dr. Ross’ biggest fan.
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George Clooney
George Clooney.Sven Arnstein/NBCU Photo Bank/NBCUniversal via Getty

Sven Arnstein/NBCU Photo Bank/NBCUniversal via Getty
George Clooney, who was crowned PEOPLE’s Sexiest Man in 1997 and 2006, appeared as Dr. Doug Ross on the medical dramaERstarting in 1994. Twelve years after the show wrapped, the cast came together for an epic Zoom reunion and Clooney admitted that his wife, Amal,is not Dr. Ross’ biggest fan.
06of 15Matthew McConaugheyMatthew McConaughey.Columbia Pictures/GettyFor the 2001 romantic comedy,The Wedding Planner, PEOPLE’s soon-to-be2005 Sexiest Man Alivewas tapped for the role of Dr. Steve “Eddie” Edison — a pediatrician who falls in love withJennifer Lopez’s Mary Fiore.
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Matthew McConaughey
Matthew McConaughey.Columbia Pictures/Getty

Columbia Pictures/Getty
For the 2001 romantic comedy,The Wedding Planner, PEOPLE’s soon-to-be2005 Sexiest Man Alivewas tapped for the role of Dr. Steve “Eddie” Edison — a pediatrician who falls in love withJennifer Lopez’s Mary Fiore.
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Richard Gere

Not only hasGerebeen named sexiest twice (once in 1993 alongsideCindy Crawfordas the sexiest couple, and again in 1999 solo), he’s also played a doctor more than once! In 2000’sDr. T & the Women,he portrayed a successful gynecologist, and in the 2008 film adaptation of Nicholas Sparks’Nights in Rodanthe,he played Dr. Paul Flanner.
08of 15Harrison FordHarrison Ford.Warner Brothers/courtesy Everett Collection1998’s Sexiest Man AliveFordis another who has put on a white coat more than once for a role. In 1988’sFrantic, he played Dr. Richard Walker, a doctor whose wife is abducted from their hotel while they’re in Paris for a medical conference.In another ill-fated tale, 1993’sThe Fugitive(above), his Dr. Richard Kimble is wrongfully arrested for murder in the death of his wife. And in 2010, he starred alongsideBrendan FraserandKeri RussellinExtraordinary Measures,in which he played a scientist recruited to help two parents find a cure for their children’s rare illnesses.He’s a doctor again in his latest role, bringing laughs as therapist Dr. Paul Rhoades onShrinking.
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Harrison Ford
Harrison Ford.Warner Brothers/courtesy Everett Collection

Warner Brothers/courtesy Everett Collection
1998’s Sexiest Man AliveFordis another who has put on a white coat more than once for a role. In 1988’sFrantic, he played Dr. Richard Walker, a doctor whose wife is abducted from their hotel while they’re in Paris for a medical conference.
In another ill-fated tale, 1993’sThe Fugitive(above), his Dr. Richard Kimble is wrongfully arrested for murder in the death of his wife. And in 2010, he starred alongsideBrendan FraserandKeri RussellinExtraordinary Measures,in which he played a scientist recruited to help two parents find a cure for their children’s rare illnesses.
He’s a doctor again in his latest role, bringing laughs as therapist Dr. Paul Rhoades onShrinking.
09of 15Pierce BrosnanPierce Brosnan.Anna Kooris/HuluIn the 2021 horror film,False Positive,2001’s Sexiest Man Aliveportrayed a sinister gynecologist.
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Pierce Brosnan
Pierce Brosnan.Anna Kooris/Hulu

Anna Kooris/Hulu
In the 2021 horror film,False Positive,2001’s Sexiest Man Aliveportrayed a sinister gynecologist.
10of 15Hugh JackmanHugh Jackman.Warner Bros Pictures/Kobal/ShutterstockIn 2006’sThe Fountain, which takes place in the past, present and future,2008’s Sexiest Man Aliveplayed varying roles — depending on where in time he was — but in present day, was a neurosurgeon on a journey to save his wife.
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Hugh Jackman
Hugh Jackman.Warner Bros Pictures/Kobal/Shutterstock

Warner Bros Pictures/Kobal/Shutterstock
In 2006’sThe Fountain, which takes place in the past, present and future,2008’s Sexiest Man Aliveplayed varying roles — depending on where in time he was — but in present day, was a neurosurgeon on a journey to save his wife.
11of 15Jude LawJude Law.Di Bonaventura Pictures/Kobal/Shutterstock2004’s Sexiest Man Aliveplayed psychiatrist Jonathan Banks in the 2013 thriller,Side Effects,alongsideRooney Mara,Channing Tatum(a fellow Sexiest Man!) andCatherine Zeta-Jones.
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Jude Law
Jude Law.Di Bonaventura Pictures/Kobal/Shutterstock

Di Bonaventura Pictures/Kobal/Shutterstock
2004’s Sexiest Man Aliveplayed psychiatrist Jonathan Banks in the 2013 thriller,Side Effects,alongsideRooney Mara,Channing Tatum(a fellow Sexiest Man!) andCatherine Zeta-Jones.
12of 15Tom CruiseTom Cruise.Warner Bros/courtesy Everett Collection / Everett CollectionIn the 1999 sexual drama,Eyes Wide Shut, PEOPLE’s1990 Sexiest Man Aliveplayed Dr. Bill Harford opposite his then real-life wife,Nicole Kidman.
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Tom Cruise
Tom Cruise.Warner Bros/courtesy Everett Collection / Everett Collection

Warner Bros/courtesy Everett Collection / Everett Collection
In the 1999 sexual drama,Eyes Wide Shut, PEOPLE’s1990 Sexiest Man Aliveplayed Dr. Bill Harford opposite his then real-life wife,Nicole Kidman.
13of 15Ryan ReynoldsRyan Reynolds.20thCentFox/Courtesy Everett CollectionBefore he launched into stardom, the Sexiest Man Alive of 2010’s big break came on the sitcom,Two Guys, a Girl and a Pizza Place,from 1998 to 2001. On the show,Reynoldsplayed Michael “Berg” Bergen, working at a pizza parlor and becoming a med student.
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Ryan Reynolds
Ryan Reynolds.20thCentFox/Courtesy Everett Collection

20thCentFox/Courtesy Everett Collection
Before he launched into stardom, the Sexiest Man Alive of 2010’s big break came on the sitcom,Two Guys, a Girl and a Pizza Place,from 1998 to 2001. On the show,Reynoldsplayed Michael “Berg” Bergen, working at a pizza parlor and becoming a med student.
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Patrick Swayze

1991’s Sexiest Man Alive, the lateSwayze, stepped into the role of Dr. Max Lowe in 1992’sCity of Joy. In the film, Dr. Lowe brings his medical training to Calcutta after a tragedy in his operating room in Houston.
15of 15Mark HarmonMark Harmon.Jack Hamilton/NBCU Photo Bank/NBCUniversal via GettyHarmonwas named Sexiest Man Alive in 1986, right around the time the actor ended his tenure as Dr. Robert Caldwell onSt. Elsewhere— where he appeared for three seasons alongside fellow Sexiest Man Alive, Denzel Washington.
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Mark Harmon
Mark Harmon.Jack Hamilton/NBCU Photo Bank/NBCUniversal via Getty

Harmonwas named Sexiest Man Alive in 1986, right around the time the actor ended his tenure as Dr. Robert Caldwell onSt. Elsewhere— where he appeared for three seasons alongside fellow Sexiest Man Alive, Denzel Washington.
source: people.com