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A adult female who survivedcancerwas infect with the novel coronavirus for nearly a class , in the longest - ever account case of COVID-19 , agree to a Modern survey .
The 47 - year - old woman was first hospitalized with COVID-19 in spring 2020 at the National Institutes of Health ( NIH ) in Maryland , Science Magazine report . Her infection persist in for 335 days and was cover through repeated positive COVID-19 tests and lingering symptom that call for supplemental oxygen at home .
Though her test showed up overconfident , viruslevels in her body were barely detectable for months after her initial contagion . Then , in March 2021 , her computer virus level transfix again . Researchers equate the genome from sample collected during her original contagion with the more recent one and found that the virus was the same . In other words , this patient role was n’t reinfected , but had continue to hold the same virus for almost a year , the authors reported in a study post as a preprint onmedRxiv , which has yet to be peer - critique .
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The novel coronavirus was in all likelihood able to remain so long in the woman ’s body because she had a compromise immune system due to previous treatment of lymphoma , a cancer in part of the immune scheme , Science Magazine describe . The patient role had been successfully treated with CAR T - cellular phone therapy about three years ago , which soften her immune system by depleting her soundbox of most of its vitamin B cells , immune systemcells that makeantibodies .
There have been sporadic reports on immunocompromised patient who shed the virus for much longer than expected , such as a patient role with leukemia in Washington whoshed the computer virus for 70 24-hour interval , but this is the longest report case .
Cases of infection in patient role with weakened resistant system " give you a window on how the virus explores the genetic distance , " older bailiwick author Elodie Ghedin , a molecular virologist at the NIH , evidence Science Magazine . By analyze samples from this patient and other people with chronic infections , researchers can see how the virus evolves .
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In the coronavirus that was try from the patient with lymphoma , the researchers found two genetic deletions ( a variation that erases parts of the genome ) , one in some of the genes that code for the computer virus ’s spike protein ( the arm the computer virus uses to overrun human cells ) and the other , a vast deletion outside of the spike protein — an area that ’s largely unknown due to deficiency of study . Other researchers had discovered a exchangeable cut in that orbit outside the spike protein in patient with chronic infections , Science Magazine report .
Chronic infections are uncommon , but they can direct to new variants , as the computer virus has more fourth dimension and space to evolve within a body with a weakened immune system . The patient role with lymphoma , who was hospitalize again and treated for the COVID-19 infection , finally cleared the virus and has had multiple negative COVID-19 tests since April .
Readmore about the case studyat Science Magazine .
Originally published on Live Science .
